Research Theme: Generation, cryopreservation and phenotyping of murine mutant models of human diseases (Infrafrontier-Emma European Infrastructure).
Keywords: mouse mutant, disease model
Member of Technical Working Group-Information Technology/Data Curation of European Mouse Mutant Archive (EMMA) and Infrafrontier (ESFRI Roadmap Landmark/MIUR Roadmap&PNIR Project; www.infrafrontier.eu) Research Infrastructures, since their establishment upon CNR’s initiative, as leading collaborative projects of major European and extra-European biomedical research Institutions, with continued support by European Framework Programmes 4-7 ad Horizon 2020.
Member of Technical Working Group-Information Technology/Data Curation of International Mouse Phenotyping Consortium (IMPC; www.mousephenotype.org; G7 Science Ministers’ Mature Global Initiative) and European Open Life Science Cloud (www.eosc-life.eu; Horizon2020 Open Science Cloud Initiative).
Member of international projects, initiatives and workgroups at the A. Buzzati-Traverso
Campus, Monterotondo since its establishment in 1996 by CNR, EMBL and the other cooperating international research Institutions.
Education:
2008 Doctor of Science, magna cum laude, European Molecular Biology Laboratory (EMBL) and Ruprecht-Karls University of Heidelberg, Germany
2002 Laurea degree, cum laude, Biological Sciences, Tor Vergata University of Rome, Italy
Positions:
Since September 2013, Technologist, Institute of Biochemistry and Cell Biology, Monterotondo RM, Italy
2009-2013 Post-doctoral fellow, Institute of Cell Biology and Neurobiology, Monterotondo RM, Italy
2003-2008 PhD student, EMBL Mouse Biology Unit Monterotondo RM, Italy
Member, Technical Working Group-Information Technology/Data Curation:
- European Mouse Mutant Archive (EMMA) Research Infrastructure
- Infrafrontier Research Infrastructure, ESFRI Roadmap Landmark/MIUR Roadmap&PNIR Priority Project
- International Mouse Phenotyping Consortium (IMPC), G7 Science Ministers’ Selected Mature Global Initiative
- European Open Life Science Cloud (EOSC-Life) Horizon2020 Open Science Cloud Initiative
Identification of genetic elements in metabolism by high-throughput mouse phenotyping
Rozman J et al. IMPC Consortium (…Massimi M,…)
Nat Commun. 2018, PMID 29348434
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.
Bowl MR et al. IMPC Consortium (…Massimi M,…)
Nat Commun. 2017, PMID 29026089
INFRAFRONTIER–providing mutant mouse resources as research tools for the international scientific community.
INFRAFRONTIER Consortium (…Massimi M,…)
Nucleic Acids Res. 2015, PMID 25414328
EMMA–mouse mutant resources for the international scientific community.
Wilkinson P, Sengerova J, Matteoni R, Chen CK, Soulat G, Ureta-Vidal A, Fessele S, Hagn M, Massimi M, Pickford K, Butler RH, Marschall S, Mallon AM, Pickard A, Raspa M, Scavizzi F, Fray M, Larrigaldie V, Leyritz J, Birney E, Tocchini-Valentini GP, Brown S, Herault Y, Montoliu L, de Angelis MH, Smedley D.
Nucleic Acids Res. 2010, PMID 19783817
Profilin2 contributes to synaptic vesicle exocytosis, neuronal excitability, and novelty-seeking behavior.
Pilo Boyl P, Di Nardo A, Mulle C, Sassoè-Pognetto M, Panzanelli P, Mele A, Kneussel M, Costantini V, Perlas E, Massimi M, Vara H, Giustetto M, Witke W.
EMBO J. 2007, PMID 17541406
Member, Technical Working Group-Information Technology/Data Curation
European Union’s Horizon2020 and FP7 Programmes Project Grants:
– INFRAFRONTIER2020 (H2020 Grant n. 730879) 2017-2020
– IPAD-MD (H2020 Grant n. 653961) 2015-2019
– INFRAFRONTIER-I3 (FP7 Grant n. 312325) 2013-2016
– InfraCOMP (FP7 Grant n. 284501) 2011-2014
– INFRAFRONTIER Prep. Phase (FP7 Grant n. 211404) 2008-2012 (coordinator: INFRAFRONTIER RI, Helmholtz Zentrum Muenchen)
– European Open Life Science Cloud-EOSC-Life (H2020 Grant n. 824087) 2019-2023
(coordinator: ELIXIR RI, EMBL-EBI Hinxton)
Member, Technical Working Group-Information Technology/Data Curation
European Union’s Framework Programmes Project Grants for European Mouse Mutant Archive (EMMA) Research Infrastructure and related projects
www.infrafrontier.eu
www.infrafrontier.eu/infrafrontier-research-infrastructure/organisation/european-mouse-mutant-archive
www.eosc-life.eu